Clinical significance of IgA deficiency.

Clinical significance of IgA deficiency

IgA is one of the five classes of immunoglobulin found in biological fluids. It is the major secretory immunoglobulin and is widely distributed in all mucosal secretions as a dimeric molecule linked by a joining chain and a third molecule, the secretory piece. The dimeric form is resistant to proteolytic digestion and IgA antibodies are important in the protection of mucous membranes against in...

Clinical significance of IgA deficiency.

IgA is one of the five classes of immunoglobulin found in biological fluids. It is the major secretory immunoglobulin and is widely distributed in all mucosal secretions as a dimeric molecule linked by a joining chain and a third molecule, the secretory piece. The dimeric form is resistant to proteolytic digestion and IgA antibodies are important in the protection of mucous membranes against in...

IgA Nephropathy and Significance of Immunostaining Data

Clinical significance of IgG subclass deficiency.

Clinical significance of hyper-IGA in a pediatric laboratory series

Introduction Very high levels of one or more classes of immunoglobulins can be found in children with various clinical conditions. Diagnostic protocols have been developed for defined forms of IgG, IgM or IgE hypergammaglobulinemia, which could be the expression of both chronic inflammatory disease and primary immunodeficiency syndromes. In contrast, except for well described conditions such as...